mRNA Therapeutics Global Market Report Outlook to 2028 – A $21 Billion Market by 2028, with Decline of -8.6% Since 2022

DUBLIN, Dec. 29, 2023 /PRNewswire/ — The “mRNA: Therapeutics and Global Markets” report has been added to  ResearchAndMarkets.com’s offering.

The global market for mRNA therapeutics reached $60 billion in 2022 and is estimated to reach $21 billion by the end of 2028. It is expected to decline at the CAGR of -8.6% during the forecast period. The decline, which stems from the end of COVID-19 pandemic, should be mitigated by the introduction of new drugs during the forecast period.

The COVID-19 pandemic created a niche market for mRNA therapeutics, particularly vaccines. Developed countries used mRNA vaccines for protection against the severe acute respiratory syndrome (SARS)-CoV-2. The fast-paced development of mRNA vaccines was possible due to advancement in sequencing as well as two decades of previous research on mRNA drugs. mRNA drugs should become a major segment of vaccines and therapeutics.

The mechanism of action of mRNA vaccine is like that elucidated by the protein-based vaccines. The mRNA particle, which is inserted into a healthy patient, carries the code for an antigen (a small piece of protein found on the virus’s outer membrane). Viral proteins are produced via the mRNA code. The body recognizes it as a foreign material and produces antibodies necessary for the protection against the diseases.

Key factors driving the mRNA global market include the increasing number of pandemics and epidemic diseases. In the past 20 years, the world has experienced the two epidemics: severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS); and the pandemic COVID-19. These situations highlighted the need for technologies like mRNA that are easy to produce and upscale quickly. The COVID-19 pandemic pushed mRNA therapeutics to the forefront of the pharma and bio-pharma industries.

Another key growth factor is the pharmaceutical industry’s investment in the mRNA segment. Large pharmaceutical companies are seeking innovative drugs that have limited side effects. mRNA presents one such opportunity. Also, private investments are increasing in this segment, driven by the COVID-19 pandemic.

However, the market also is facing a few challenges, such as lack of standard regulations that affect a different class of therapeutics. This leads to confusion for new and existing players for which pathway to follow. Existing and new technologies, such as protein and CRISP, respectively, also pose competition.

The pipeline of mRNA drugs is robust. Under favorable conditions, a drug should enter the market by late 2024 or early 2025. Currently, the majority of drugs in the pipeline target infectious diseases or are being developed as vaccines. Also, therapeutic drugs target cancer treatment. Some drugs have received fast-track status from the FDA, increasing the pace of those clinical trials due to their promising results. Drug trials using mRNA vaccines are showing efficacy in the range of 70% to 85%. There are 2 influenzas vaccines which are, under phase 3 clinical trials and will be commercialized during the forecast period.

Report Scope

This report focuses on the mRNA therapeutics market and includes the types of mRNA and their application in therapy. Also, the report focuses on the patent analysis and clinical trial analysis of mRNA. The report also portrays the trends and dynamics affecting the market during the study period. The study covers market projections through 2028 and profiles major market players.

The Report Includes

37 data tables and 27 additional tablesAn overview of the global market related to mRNA therapeuticsIn-depth analysis of global market trends, featuring historical revenue data for 2021 and 2022, estimated figures for 2023, forecasts for 2028, and projections of compound annual growth rates (CAGRs) through 2028Evaluation of the current market and revenue growth prospects specific to mRNA therapeutics, accompanied by a market share analysis by therapeutic type and geographical regionCoverage of the pandemic threats, therapeutic developments, and new technologies in the marketDiscussion of the advantages of mRNA over proteinand DNA-based delivery systems, demographic and economic trends, and outlook for the mRNA therapeutics marketInformation on prophylactic vaccines, vaccine discovery and development, and R&D activitiesAnalysis of the various therapeutics as well as promising vaccines intended for the prevention and treatment of chronic and infectious diseasesAssessment of regulatory structure, pricing and reimbursement scenarios, the pipeline for new molecules and therapeuticsMarket share analysis of the key companies and mergers & acquisitions, joint ventures, collaborations, and partnershipsProfiles of leading market participants

Key Topics Covered:

Chapter 1 Introduction

Chapter 2 Summary and Highlights

Chapter 3 Market Overview

Evolution of RNA TherapeuticsHistory of RNA TherapeuticsDevelopment of RNA Therapeutics and TypesDNA Therapeutics vs. RNA TherapeuticsClinical Need for RNA TherapeuticsIncreasing Disease Population and Economic BurdenLimitations of Traditional TherapeuticsTherapeutic Limitations of BiologicsPoor Management of Chronic DiseasesLimited Treatment for Rare DiseasesRNA TherapeuticsAntisense Oligonucleotide (ASO) as TherapeuticsSmall Interfering RNA (siRNA) as TherapeuticsmiRNA as TherapeuticsAptamers as TherapeuticsmRNA as TherapeuticsManufacturing RNA-Based BiopharmaceuticalsChromatographic Purification StepsDelivery of RNA TherapeuticsPolymer Conjugation/Chemical ModificationEncapsulationLipid-Based NanoparticlesPolymer NanomaterialsSilica NanoparticlesCarbon and Gold NanomaterialsGalNAcInstitution and Hospital-Based RNA TherapeuticsRegulatory Influence on the Market for RNA TherapeuticsImpact of COVID-19

Chapter 4 Market Dynamics

Chapter 5 Target Disease and Disorders

Chapter 6 Pipeline and Clinical Trial Analysis

Chapter 7 Market Breakdown by Product

Chapter 8 Market Breakdown by Region

Chapter 9 Emerging Technologies and Developments

NanoparticlesModified mRNAAutomated mRNA Synthesis KitsBio Platforms

Chapter 10 Patent Analysis

Chapter 11 Outlook for Mergers & Acquisitions, and Venture Funding

Chapter 12 Competitive Intelligence

Chapter 13 Company Profiles

Arctur U.S. TherapeuticsBiontechCurevacGennova BiopharmaceuticalsMerckModernaNutcracker TherapeuticsOmega TherapeuticsStrand TherapeuticsVaxess Technologies

For more information about this report visit https://www.researchandmarkets.com/r/9zpkkt

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